Waters and Nonlinear Dynamics jointly develop a new generation of solutions for research on large-scale complex data sets

Analytical science and informatics programs are combined to promote proteomics and metabolomics research

Milford, Massachusetts-On August 2, 2012, Waters Corporation (WAT: NYSE) and Nonlinear Dynamics Co., Ltd. have signed an agreement that the two parties will jointly develop solutions to deal with the large Large-scale complex data set.

The collaboration between Waters and Nonlinear Dynamics on the Waters omics research platform based on TransOmics ™ software was first announced at the ASMS Conference on Mass Spectrometry and Allied Topics in Vancouver this May. The Waters® SYNAPT® G2 -S HDMS is organically integrated with TransOmics informatics software exclusively developed by Nonlinear Dynamics for Waters.

The Waters omics research platform includes two sets of solutions based on TransOmics informatics software:

· Proteomics solution containing Waters nanoACQUITY UPLC® and SYNAPT® G2-S HDMS for bottom-up analysis of complex samples.

· Metabolomics solution containing Waters ACQUITY® UPLC I-Class and SYNAPT G2-S HDMS for routine screening of large-scale samples.

Waters launched SYNAPT® HDMS ™ high-definition mass spectrometry in 2007, introducing ion mobility separation technology to mass spectrometry for the first time.

Synapt HDMS system is widely used in the field of small molecule research, protein identification, metabolite identification and biopharmaceuticals. At present, it is still the only mass spectrometer on the market with high-efficiency ion mobility measurement and separation. , Charge and mass to separate. This ability to separate based on differences in molecular configuration improves the selectivity of analysis and sample clarity, so scientists can obtain more sample information, including components that cannot be seen on traditional mass spectrometers.

"Biological samples are too complicated. When the analytical instruments meet the biological research requirements for sensitivity and analytical technology specificity, the processing of experimental data also brings great challenges to scientists." Waters Pharmaceutical and Life Sciences R & D Department is responsible Dr. James Langridge said, "We believe that by collaborating with Nonlinear Dynamics, our solution can help scientists effectively cope with this situation and promote the speed of research and development."

"I am very pleased to see this exciting collaboration that combines the latest mass spectrometry technology with world-renowned data analysis software," said Will Dracup, executive chairman of Nonlinear Dynamics. "Now researchers are facing how The challenge of dealing with huge and complex data sets. That is to say, must be able to obtain intuitive, easy to read and reliable data results. Waters ion mobility technology can produce a large number of very valuable, data-rich omics data sets, Nonlinear The software developed specifically highlights the potential advantages and value of ion mobility technology. "

Omics research, whether it is proteomics or metabolomics, the common purpose is to understand the relationship between proteins and metabolites in order to better understand the specific physiological state of the disease or body. The Waters omics research platform is ideal for researchers in the fields of pharmaceutical and life sciences, food and clinical research to conduct interdisciplinary research.

The omics platform product UPLC® / SYNAPT G2-S HDMS based on TransOmics software released at the ASMS American Mass Spectrometry Annual Conference will be shipped in the fourth quarter of this year.

About Nonlinear Dynamics ()

Nonlinear Dynamics was founded by Will Dracup in 1989. It has developed the Progenesis data analysis software series, which is innovative and breakthrough. It can especially help meet the challenges faced by today's protein and metabolomics researchers.

The basic analysis concept proposed by Nonlinear for the Progenesis software series helps scientists visualize their complex data and draw reliable conclusions that can be replicated between laboratories. This method has been applied to LC-MS and two-dimensional gel electrophoresis data analysis.

Nonlinear sells and supports products through its headquarters in the United Kingdom and offices in the United States and a global network of partners.

About Waters Corporation ()

For more than 50 years, Waters Corporation (NYSE: WAT) has made significant progress in the fields of medical services, environmental management, food safety and global water quality monitoring by providing practical and sustainable innovations, thereby creating business for laboratory-related institutions Advantage.

As the pioneer of a series of separation science, laboratory information management, mass spectrometry and thermal analysis technologies, Waters ’major breakthroughs and laboratory solutions have created a lasting platform for customers’ success.

With a revenue of US $ 1.85 billion in 2011, Waters will continue to lead customers around the world to explore science and achieve outstanding achievements.

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