Editor's note: The cells in the human body can be transformed into each Other? Before the scientist made this attempt, the editor thought that this idea was a little bit wrong. Bone marrow mesenchymal stem cells (MSC) are important members of the stem cell family, derived from early mesoderm and ectoderm. Brain cells mainly include neurons and glial cells, similar to different functions in automobiles. The two parts are totally irrelevant. How can we achieve transformation? A few days ago, American scientists uncovered this mystery for us. According to a recent report from the American Society for the Advancement of Science, scientists at the Scripps Research Institute (TSRI) have found a way to directly convert bone marrow stem cells into brain cells. The results of this study demonstrate the potential of antibodies as a universal operator of cell functions. The researchers found that the antibodies cultivated in the laboratory can activate growth-stimulating antibodies in bone marrow cells, which eventually induce bone marrow stem cells (usually developed into white blood cells) into neural precursor cells (brain cells that are about to mature). This kind of cell therapy, which extracts the patient's own cells, because it hardly encounters the immune rejection characteristics of the human body, it is expected to treat spinal cord, stroke and other diseases of the body. This new technology will make it easier and more Safe conversion technology becomes possible. As early as 2003, American scientists proposed that underdeveloped bone marrow stem cells could be transferred to the human brain on their own and could be transformed into fully functional brain cells. These scientists discovered this phenomenon when pathologically dissecting some female dead. These female deceased all had bone marrow transplants before they died. The transplanted bone marrow comes from male donors. They discovered the Y chromosome in the brain cells of these female deceased. The Y chromosome only exists in the cells of males, so it is judged that these Y chromosome-bearing cells come from transplanted bone marrow stem cells. Based on this, they pointed out that if they can find a way to guide stem cells into the damaged areas of brain cells or nerve cells, these brain damage or nerve damage can be repaired. Of course, this new discovery was also opposed by other scientists. They pointed out that bone marrow stem cells "migrate" to the brain, and there is also the risk of bringing harmful substances or even viruses into the brain. If not controlled well, it may lead to harmful reactions of the immune system. Ten years later, it is clear that the latest research has alleviated the concerns of some scientists. In this new study, researchers have improved existing technologies so that antibody proteins produced by a given cell can form a physical anchor with the outer cell membrane near the target receptor. Limiting the activity of antibodies allows researchers to use large antibody libraries to quickly screen out antibodies for specific activities. Thanks to this improved technology, scientists can screen antibody libraries containing millions of antibodies in a few days. Richard Lerner, a professor in the Department of Cellular and Molecular Biology at SRI, said that turning bone marrow cells into nerve cells by activating a single receptor is a remarkable scientific progress. Although scientists have previously been able to differentiate bone marrow stem cells into other adult cells, these methods usually require the conversion of bone marrow cells into embryonic stem cell states, which are then directed to specific adult cells by a series of complex molecules. Current cell therapies usually assume that the patient's cells can be obtained, reprogrammed and propagated in a petri dish, and then introduced into the patient's body. The newly discovered antibody can be directly injected into the patient's blood in principle. It can find a way to penetrate the bone marrow and differentiate the bone marrow mesenchymal stem cells into neural precursor cells. These neural progenitor cells will then infiltrate the brain, find the damaged area and repair it. Handle,High Quality Handle,Handle Details, Sunzhengde Hardware Mfg Co., Ltd. Sunzhengde Hardware Mfg Co., Ltd. , https://www.sunzhengde.com